Ginsengenin derivatives synthesized from 20(R)-panaxotriol: Synthesis, characterization, and antitumor activity targeting HIF-1 pathway

Ginsengenin derivatives synthesized from 20(R)-panaxotriol: Synthesis, characterization, and antitumor activity targeting HIF-1 pathway

Background: Ginseng possesses antitumor effects, and ginsenosides are considered to be one of its main active chemical components. Ginsenosides can further be hydrolyzed to generate secondary saponins, and 20(R)-panaxotriol is an important sapogenin of ginsenosides. We aimed to synthesize a new gins...

Full description

Bibliographic Details
Main Authors: Hong-Yan Guo, Yue Xing, Yu-Qiao Sun, Can Liu, Qian Xu, Fan-Fan Shang, Run-Hui Zhang, Xue-Jun Jin, Fener Chen, Jung Joon Lee, Dongzhou Kang, Qing-Kun Shen, Zhe-Shan Quan
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Journal of Ginseng Research
Subjects:
20(R)-Panaxotriol
Antitumor
Derivatives
HIF-1α
Online Access:http://www.sciencedirect.com/science/article/pii/S1226845322000306

Internet

http://www.sciencedirect.com/science/article/pii/S1226845322000306

Similar Items