Neutralizing Dromedary-Derived Nanobodies Against BotI-Like Toxin From the Most Hazardous Scorpion Venom in the Middle East and North Africa Region

Neutralizing Dromedary-Derived Nanobodies Against BotI-Like Toxin From the Most Hazardous Scorpion Venom in the Middle East and North Africa Region

Scorpion envenoming is a severe health problem in many regions causing significant clinical toxic effects and fatalities. In the Middle East/North Africa (MENA) region, Buthidae scorpion stings are responsible for devastating toxic outcomes in human. The only available specific immunotherapeutic tre...

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Bibliographic Details
Main Authors: Rahma Ben Abderrazek, Ayoub Ksouri, Faten Idoudi, Sayda Dhaouadi, Emna Hamdi, Cécile Vincke, Azer Farah, Zakaria Benlasfar, Hafedh Majdoub, Mohamed El Ayeb, Serge Muyldermans, Balkiss Bouhaouala-Zahar
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Immunology
Subjects:
Buthus occitanus tunetanus
scorpion toxin
VHH Dromedary library
phage display
nanobodies
neutralizing capacity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.863012/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.863012/full

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