Comparative Effects of Intra-Articular versus Intravenous Mesenchymal Stromal Cells Therapy in a Rat Model of Osteoarthritis by Destabilization of Medial Meniscus

Comparative Effects of Intra-Articular versus Intravenous Mesenchymal Stromal Cells Therapy in a Rat Model of Osteoarthritis by Destabilization of Medial Meniscus

Transplanted mesenchymal stromal cells (MSCs) exhibit a robust anti-inflammatory and homing capacity in response to high inflammatory signals, as observed in studies focused on rheumatic diseases that target articular cartilage (AC) health. However, AC degradation in osteoarthritis (OA) does not nec...

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Bibliographic Details
Main Authors: Felipe Bruno Dias de Oliveira, Eliane Antonioli, Olívia Furiama Metropolo Dias, Jean Gabriel de Souza, Sudha Agarwal, Ana Marisa Chudzinski-Tavassi, Mario Ferretti
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:International Journal of Molecular Sciences
Subjects:
osteoarthritis
mesenchymal stromal cell
mesenchymal stem cell
intra-articular
intravenous
inflammation
Online Access:https://www.mdpi.com/1422-0067/24/21/15543

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https://www.mdpi.com/1422-0067/24/21/15543

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