In silico design of peptide inhibitors for Dengue virus to treat Dengue virus-associated infections

In silico design of peptide inhibitors for Dengue virus to treat Dengue virus-associated infections

Abstract Dengue virus is a single positive-strand RNA virus that is composed of three structural proteins including capsid, envelope, and precursor membrane while seven non-structural proteins (NS1, NS2A, NS2B, NS3A, NS3B, NS4, and NS5). Dengue is a viral infection caused by the dengue virus (DENV)....

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Bibliographic Details
Main Authors: Amar Ajmal, Muhammad Shahab, Muhammad Waqas, Guojun Zheng, Maryam Zulfat, Yousef A. Bin Jardan, Gezahign Fentahun Wondmie, Mohammed Bourhia, Ijaz Ali
Format: Article
Language:English
Published: Nature Portfolio 2024-06-01
Series:Scientific Reports
Subjects:
Peptide inhibitors
Residue scanning
MD simulation
Binding energy calculation
Online Access:https://doi.org/10.1038/s41598-024-63064-1

Internet

https://doi.org/10.1038/s41598-024-63064-1

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