Increased level of exosomal miR-20b-5p derived from hypothermia-treated microglia promotes neurite outgrowth and synapse recovery after traumatic brain injury

Increased level of exosomal miR-20b-5p derived from hypothermia-treated microglia promotes neurite outgrowth and synapse recovery after traumatic brain injury

Mild hypothermia has been proven to inhibit microglia activation after TBI. Exosomal microRNA derived from microglia played a critical role in promoting neurite outgrowth and synapse recovery. Here, we aimed to investigate the role of microRNAs in microglial exosomes after hypothermia treatment on n...

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Bibliographic Details
Main Authors: Chuanfang Wang, Yunxiang Ji, Huabin Zhang, Yongyi Ye, Guilong Zhang, Shizhen Zhang, Chengcheng Zhao, Yezhong Wang
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Neurobiology of Disease
Subjects:
Exosomes
Hypothermia
Microglia
Synapse
Traumatic brain injury
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996123000566

Internet

http://www.sciencedirect.com/science/article/pii/S0969996123000566

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