Polymorphism of virulence genes and biofilm associated with in vitro induced resistance to clarithromycin in Helicobacter pylori

Polymorphism of virulence genes and biofilm associated with in vitro induced resistance to clarithromycin in Helicobacter pylori

Abstract Background Clarithromycin-containing triple therapy is commonly used to treat Helicobacter pylori infections. Clarithromycin resistance is the leading cause of H. pylori treatment failure. Understanding the specific mutations that occur in H. pylori strains that have evolved antibiotic resi...

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Bibliographic Details
Main Authors: Naim Asyraf Rosli, Anis Rageh Al-Maleki, Mun Fai Loke, Eng Guan Chua, Mohammed Abdelfatah Alhoot, Jamuna Vadivelu
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Gut Pathogens
Subjects:
Helicobacter pylori
Whole genome sequencing
Virulence
Biofilm formation
Antibiotic resistance
Clarithromycin
Online Access:https://doi.org/10.1186/s13099-023-00579-4

Internet

https://doi.org/10.1186/s13099-023-00579-4

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