Factors influencing cell differentiation and expressions of cytochrome P450s and transporters in Caco-2 cells

Absorption, transportation, and first-pass metabolism of xenobiotics, drugs and nutrients taken orally occurs in the intestine, which is a major organ expressing cytochrome P450 enzymes (CYP) and transporters. Caco-2 is a human colon carcinoma cell line widely employed as a model for xenobiotic ab...

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Bibliographic Details
Main Authors: Nathaphon Kuncharoenwirat, Waranya Chatuphonprasert, Kanokwan Jarukamjorn
Format: Article
Language:English
Published: Prince of Songkla University 2021-06-01
Series:Songklanakarin Journal of Science and Technology (SJST)
Subjects:
Online Access:https://rdo.psu.ac.th/sjstweb/journal/43-3/26.pdf