Identification of a sub-group of critically ill patients with high risk of intensive care unit-acquired infections and poor clinical course using a transcriptomic score

Identification of a sub-group of critically ill patients with high risk of intensive care unit-acquired infections and poor clinical course using a transcriptomic score

Abstract Background The development of stratification tools based on the assessment of circulating mRNA of genes involved in the immune response is constrained by the heterogeneity of septic patients. The aim of this study is to develop a transcriptomic score based on a pragmatic combination of immu...

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Bibliographic Details
Main Authors: Maxime Bodinier, Guillaume Monneret, Marie Casimir, Aurore Fleurie, Filippo Conti, Fabienne Venet, Marie-Angélique Cazalis, Elisabeth Cerrato, Estelle Peronnet, Thomas Rimmelé, Anne-Claire Lukaszewicz, Karen Brengel-Pesce, Jean-François Llitjos
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Critical Care
Subjects:
Sepsis
Transcriptomic
Intensive care unit
Acquired infections
Personalized medicine
Online Access:https://doi.org/10.1186/s13054-023-04436-3

Internet

https://doi.org/10.1186/s13054-023-04436-3

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