Identification of a sub-group of critically ill patients with high risk of intensive care unit-acquired infections and poor clinical course using a transcriptomic score
Abstract Background The development of stratification tools based on the assessment of circulating mRNA of genes involved in the immune response is constrained by the heterogeneity of septic patients. The aim of this study is to develop a transcriptomic score based on a pragmatic combination of immu...
Main Authors: | Maxime Bodinier, Guillaume Monneret, Marie Casimir, Aurore Fleurie, Filippo Conti, Fabienne Venet, Marie-Angélique Cazalis, Elisabeth Cerrato, Estelle Peronnet, Thomas Rimmelé, Anne-Claire Lukaszewicz, Karen Brengel-Pesce, Jean-François Llitjos |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2023-04-01
|
Series: | Critical Care |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13054-023-04436-3 |
Similar Items
-
Mortality Prediction in Sepsis With an Immune-Related Transcriptomics Signature: A Multi-Cohort Analysis
by: Louis Kreitmann, et al.
Published: (2022-06-01) -
A 9-mRNA signature measured from whole blood by a prototype PCR panel predicts 28-day mortality upon admission of critically ill COVID-19 patients
by: Claire Tardiveau, et al.
Published: (2022-11-01) -
Concomitant Assessment of Monocyte HLA-DR Expression and Ex Vivo TNF-α Release as Markers of Adverse Outcome after Various Injuries—Insights from the REALISM Study
by: Frank Bidar, et al.
Published: (2021-12-01) -
Acquired Hemophilia
by: Şinasi Özsoylu
Published: (2014-12-01) -
Dysregulated expression of amino-acid and glucose transporters on circulating plasma cells in septic shock patients: a preliminary study
by: Margot Lepage, et al.
Published: (2022-10-01)