Layer‐by‐layer interleukin‐12 nanoparticles drive a safe and effective response in ovarian tumors

Layer‐by‐layer interleukin‐12 nanoparticles drive a safe and effective response in ovarian tumors

Abstract Ovarian cancer is especially deadly, challenging to treat, and has proven refractory to known immunotherapies. Cytokine therapy is an attractive strategy to drive a proinflammatory immune response in immunologically cold tumors such as many high grade ovarian cancers; however, this strategy...

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Bibliographic Details
Main Authors: Antonio E. Barberio, Sean G. Smith, Ivan S. Pires, Sonia Iyer, Ferenc Reinhardt, Mariane B. Melo, Heikyung Suh, Robert A. Weinberg, Darrell J. Irvine, Paula T. Hammond
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:Bioengineering & Translational Medicine
Subjects:
cancer immunotherapy
cytokine
drug delivery
layer‐by‐layer
nanomedicine
nanoparticle
Online Access:https://doi.org/10.1002/btm2.10453

Internet

https://doi.org/10.1002/btm2.10453

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