An alcohol extract prepared from the male flower of Eucommia ulmoides Oliv. promotes synoviocyte apoptosis and ameliorates bone destruction in rheumatoid arthritis

An alcohol extract prepared from the male flower of Eucommia ulmoides Oliv. promotes synoviocyte apoptosis and ameliorates bone destruction in rheumatoid arthritis

Abstract Background Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease dominated by synovial hyperplasia and bone destruction. The male flower of Eucommia ulmoides Oliv. (EF) has been shown to exert effects on the inflammation caused by RA. However, how EF affects synoviocyte apoptos...

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Bibliographic Details
Main Authors: Yan Zhang, Jian-Ying Wang, Hao Wang, Xiao-Yun Chen, Lei Zhang, Ying Yuan
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Chinese Medicine
Subjects:
Rheumatoid arthritis
Eucommia ulmoides Oliv.
CIA rat
Bone metabolism
NF-κB signaling pathway
Online Access:https://doi.org/10.1186/s13020-021-00522-2

Internet

https://doi.org/10.1186/s13020-021-00522-2

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