Radiotherapy delays malignant transformation and prolongs survival in patients with IDH-mutant gliomas

Radiotherapy delays malignant transformation and prolongs survival in patients with IDH-mutant gliomas

Objective: IDH-mutant lower-grade gliomas (LGGs, grade 2 or 3) eventually transform into secondary grade 4 astrocytomas (sAIDHmut/G4). Here, we sought to describe the transformation time, risk factors, and outcomes in malignant transformation of IDH-mutant LGGs. Methods: We screened data for 108 pat...

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Bibliographic Details
Main Authors: Yanwei Liu, Huiyuan Chen, Guanzhang Li, Jing Zhang, Kun Yao, Chenxing Wu, Shouwei Li, Xiaoguang Qiu
Format: Article
Language:English
Published: China Anti-Cancer Association 2022-10-01
Series:Cancer Biology & Medicine
Subjects:
lower-grade gliomas
idh mutation
radiotherapy
malignant transformation
survival
Online Access:https://www.cancerbiomed.org/content/19/10/1477

Internet

https://www.cancerbiomed.org/content/19/10/1477

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