Iron Withdrawal with DIBI, a Novel 3-Hydroxypyridin-4-One Chelator Iron-Binding Polymer, Attenuates Macrophage Inflammatory Responses

Purpose: Iron is an essential trace element for the inflammatory response to infection. In this study, we determined the effect of the recently developed iron-binding polymer DIBI on the synthesis of inflammatory mediators by RAW 264.7 macrophages and bone marrow-derived macrophages (BMDMs) in respo...

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Bibliographic Details
Main Authors: Javad Ghassemi-Rad, Wasundara Fernando, Bruce E. Holbein, David W. Hoskin
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2023-03-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-13-368.pdf