Measurement of activity of developmental signal transduction pathways to quantify stem cell pluripotency and phenotypically characterize differentiated cells

Important challenges in stem cell research and regenerative medicine are reliable assessment of pluripotency state and purity of differentiated cell populations. Pluripotency and differentiation are regulated and determined by activity of developmental signal transduction pathways (STPs). To date ac...

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Bibliographic Details
Main Authors: Laurent Holtzer, Yvonne Wesseling-Rozendaal, Wim Verhaegh, Anja van de Stolpe
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506122000976