Analysis of glycyrrhizin binding to protein HMGB1
Glycyrrhizin (GLR) is triterpenoid saponin used for the treatment of various of liver and skin diseases. GLR blocks the nucleocytoplasmic translocation of the protein HMGB1, thereby inhibiting its extracellular release and its functions as a damage-associated molecular pattern molecule. Here we have...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-09-01
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Series: | Medicine in Drug Discovery |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590098620300452 |