GPER1 promotes estrogen receptor negative breast cancer cell migration and invasion via non-genomic activation of c-Src/NF-κB/focal adhesion kinase cascade

Abstract. Breast cancer metastasis is the root cause of deaths from breast cancer. Currently, endocrine therapy resistance in estrogen receptor (ER)-positive (ER+) breast cancer remains a major clinical issue. Moreover, ER-negative (ER−) breast cancer is often associated with distant recurrence and...

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Bibliographic Details
Main Authors: Xiao-Sa Li, Qing Yan, Xing-Yan Xu, Wei-Yu Chen, Ping Li, Qiu-Ling Xiang, Xiao-Yang Xu, Xiao-Dong Fu
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2018-09-01
Series:Journal of Bio-X Research
Online Access:http://journals.lww.com/10.1097/JBR.0000000000000010