Development and statistical optimization of nefopam hydrochloride loaded nanospheres for neuropathic pain using Box–Behnken design

Development and statistical optimization of nefopam hydrochloride loaded nanospheres for neuropathic pain using Box–Behnken design

Nefopam hydrochloride (NFH) is a non-opioid centrally acting analgesic drug used to treat chronic condition such as neuropathic pain. In current research, sustained release nefopam hydrochloride loaded nanospheres (NFH-NS) were auspiciously synthesized using binary mixture of eudragit RL 100 and RS...

Full description

Bibliographic Details
Main Authors: S. Sukhbir, S. Yashpal, A. Sandeep
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Saudi Pharmaceutical Journal
Subjects:
Nefopam hydrochloride
Neuropathic pain
Box–Behnken design
Solvent diffusion
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016415000833

Internet

http://www.sciencedirect.com/science/article/pii/S1319016415000833

Similar Items