Impact of Morphine Treatment With and Without Metoclopramide Coadministration on Myocardial and Microvascular Injury in Acute Myocardial Infarction: Insights From the Randomized MonAMI Trial

Impact of Morphine Treatment With and Without Metoclopramide Coadministration on Myocardial and Microvascular Injury in Acute Myocardial Infarction: Insights From the Randomized MonAMI Trial

Background Intravenous morphine administration can adversely affect platelet inhibition induced by P2Y12 receptor inhibitors after acute myocardial infarction. In contrast, some evidence suggests that opioid agonists may have cardioprotective effects on the myocardium. The aim of this prospective, r...

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Bibliographic Details
Main Authors: Thomas Stiermaier, Philipp Schaefer, Roza Meyer‐Saraei, Mohammed Saad, Suzanne de Waha‐Thiele, Janine Pöss, Georg Fuernau, Tobias Graf, Thomas Kurz, Alex Frydrychowicz, Jörg Barkhausen, Steffen Desch, Holger Thiele, Ingo Eitel
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
infarct size
microvascular injury
morphine
myocardial infarction
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.018881

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.120.018881

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