The Group A Streptococcal Vaccine Candidate VAX-A1 Protects against Group B <i>Streptococcus</i> Infection via Cross-Reactive IgG Targeting Virulence Factor C5a Peptidase

The Group A Streptococcal Vaccine Candidate VAX-A1 Protects against Group B <i>Streptococcus</i> Infection via Cross-Reactive IgG Targeting Virulence Factor C5a Peptidase

Group B <i>Streptococcus</i> (<i>Streptococcus agalactiae</i> or GBS) is the leading infectious cause of neonatal mortality, causing roughly 150,000 infant deaths and stillbirths annually across the globe. Approximately 20% of pregnant women are asymptomatically colonized by...

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Bibliographic Details
Main Authors: Sinead McCabe, Elisabet Bjånes, Astrid Hendriks, Zhen Wang, Nina M. van Sorge, Lucy Pill-Pepe, Leslie Bautista, Ellen Chu, Jeroen D. C. Codée, Jeff Fairman, Neeraj Kapoor, Satoshi Uchiyama, Victor Nizet
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Vaccines
Subjects:
group A <i>Streptococcus</i>
<i>Streptococcus pyogenes</i>
group B <i>Streptococcus</i>
<i>Streptococcus agalactiae</i>
vaccine
C5a peptidase
Online Access:https://www.mdpi.com/2076-393X/11/12/1811

Internet

https://www.mdpi.com/2076-393X/11/12/1811

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