Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-κB pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of L-acetylcarnitine

<p>Abstract</p> <p>L-acetylcarnitine (LAC), a drug utilized for the treatment of neuropathic pain in humans, has been shown to induce analgesia in rodents by up-regulating the expression of metabotropic glutamate receptor 2 (mGlu2) in dorsal root ganglia (DRG). We now report that L...

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Bibliographic Details
Main Authors: Nicoletti Ferdinando, Morales Maria Elena P, De Petris Laura, Copani Agata, Chiechio Santina, Gereau Robert W
Format: Article
Language:English
Published: SAGE Publishing 2006-06-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/2/1/20