Electrochemical, spectroscopic, and molecular docking studies of the interaction between the anti-retroviral drug indinavir and dsDNA

In this study, an electrochemical DNA biosensor was developed using a straightforward methodology to investigate the interaction of indinavir with calf thymus double-stranded deoxyribonucleic acid (ct-dsDNA) for the first time. The decrease in the oxidation signals of deoxyguanosine (dGuo) and deoxy...

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Bibliographic Details
Main Authors: Fariba Mollarasouli, Burcu Dogan-Topal, Mehmet Gokhan Caglayan, Tugba Taskin-Tok, Sibel A. Ozkan
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177920310443