BCL-2 Proteins in Pathogenesis and Therapy of B-Cell Non-Hodgkin Lymphomas

The ability to inhibit mitochondrial apoptosis is a hallmark of B-cell non-Hodgkin lymphomas (B-NHL). Activation of mitochondrial apoptosis is tightly controlled by members of B-cell leukemia/lymphoma-2 (BCL-2) family proteins via protein-protein interactions. Altering the balance between anti-apopt...

Full description

Bibliographic Details
Main Authors: Magdalena Klanova, Pavel Klener
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/4/938