Vitamin B6 prevents isocarbophos-induced vascular dementia in rats through N-methyl-D-aspartate receptor signaling

Vitamin B6 prevents isocarbophos-induced vascular dementia in rats through N-methyl-D-aspartate receptor signaling

Background: We have previously reported that the long-term exposure of organophosphorus induces vascular dementia (VD) in rats. As a coenzyme, vitamin B6 is mainly involved in the regulation of metabolisms. Whether vitamin B6 improves VD remains unknown. Methods: The model of VD was induced by feedi...

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Bibliographic Details
Main Authors: Peng Li, Mo-Li Zhu, Guo-Pin Pan, Jun-Xiu Lu, Fan-Rong Zhao, Xu Jian, Li-Ying Liu, Guang-Rui Wan, Yuan Chen, Song Ping, Shuang-Xi Wang, Chang-Ping Hu
Format: Article
Language:English
Published: Taylor & Francis Group 2018-02-01
Series:Clinical and Experimental Hypertension
Subjects:
hippocampus
n-methyl-d-aspartate receptor
organophosphorus
vascular dementia
vitamin b6
Online Access:http://dx.doi.org/10.1080/10641963.2017.1356844

Internet

http://dx.doi.org/10.1080/10641963.2017.1356844

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