Inference of relationships in population data using identity-by-descent and identity-by-state.

It is an assumption of large, population-based datasets that samples are annotated accurately whether they correspond to known relationships or unrelated individuals. These annotations are key for a broad range of genetics applications. While many methods are available to assess relatedness that inv...

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Bibliographic Details
Main Authors: Eric L Stevens, Greg Heckenberg, Elisha D O Roberson, Joseph D Baugher, Thomas J Downey, Jonathan Pevsner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3178600?pdf=render