Cathepsin D—Managing the Delicate Balance

Cathepsin D—Managing the Delicate Balance

Lysosomal proteases play a crucial role in maintaining cell homeostasis. Human cathepsin D manages protein turnover degrading misfolded and aggregated proteins and favors apoptosis in the case of proteostasis disruption. However, when cathepsin D regulation is affected, it can contribute to numerous...

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Bibliographic Details
Main Authors: Olja Mijanovic, Anastasiia I. Petushkova, Ana Brankovic, Boris Turk, Anna B. Solovieva, Angelina I. Nikitkina, Sergey Bolevich, Peter S. Timashev, Alessandro Parodi, Andrey A. Zamyatnin
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Pharmaceutics
Subjects:
cathepsin D
lysosome
regulated cell death
neurodegenerative disease
malignant tumor
diabetes
Online Access:https://www.mdpi.com/1999-4923/13/6/837

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https://www.mdpi.com/1999-4923/13/6/837

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