DNA Methylation Signatures Predict Cytogenetic Subtype and Outcome in Pediatric Acute Myeloid Leukemia (AML)

DNA Methylation Signatures Predict Cytogenetic Subtype and Outcome in Pediatric Acute Myeloid Leukemia (AML)

Pediatric acute myeloid leukemia (AML) is a heterogeneous disease composed of clinically relevant subtypes defined by recurrent cytogenetic aberrations. The majority of the aberrations used in risk grouping for treatment decisions are extensively studied, but still a large proportion of pediatric AM...

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Bibliographic Details
Main Authors: Olga Krali, Josefine Palle, Christofer L. Bäcklin, Jonas Abrahamsson, Ulrika Norén-Nyström, Henrik Hasle, Kirsi Jahnukainen, Ólafur Gísli Jónsson, Randi Hovland, Birgitte Lausen, Rolf Larsson, Lars Palmqvist, Anna Staffas, Bernward Zeller, Jessica Nordlund
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Genes
Subjects:
DNA methylation
pediatric AML
acute myeloid leukemia
classification
450k array
epigenetics
Online Access:https://www.mdpi.com/2073-4425/12/6/895

Internet

https://www.mdpi.com/2073-4425/12/6/895

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