Randomized controlled multicentre study of albumin replacement therapy in septic shock (ARISS): protocol for a randomized controlled trial

Randomized controlled multicentre study of albumin replacement therapy in septic shock (ARISS): protocol for a randomized controlled trial

Abstract Background Albumin is a key regulator of fluid distribution within the extracellular space and has several properties beyond its oncotic activity. The accumulating evidence suggests that supplementation of albumin may provide survival advantages only when the insult is severe as in patients...

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Main Authors: Yasser Sakr, Michael Bauer, Axel Nierhaus, Stefan Kluge, Ulricke Schumacher, Christian Putensen, Falk Fichtner, Sirak Petros, Christian Scheer, Ulrich Jaschinski, Ivan Tanev, David Jacob, Norbert Weiler, P. Christian Schulze, Fritz Fiedler, Barbara Kapfer, Frank Brunkhorst, Ingmar Lautenschlaeger, Katja Wartenberg, Stefan Utzolino, Josef Briegel, Onnen Moerer, Petra Bischoff, Alexander Zarbock, Michael Quintel, Luciano Gattinoni, on behalf of SepNet - Critical Care Trials Group
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Trials
Subjects:
Septic shock
Fluid resuscitation
Albumin
Online Access:https://doi.org/10.1186/s13063-020-04921-y

Internet

https://doi.org/10.1186/s13063-020-04921-y

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