Double trouble: Unmasking two hook effects on Siemens Atellica® - Total PSA and total hCG assays
The “hook effect” or “prozone phenomenon” occurs when the concentration of a particular analyte saturates the antibodies used in the test, resulting in falsely low or negative results despite the presence of high analyte concentrations. We report two recent cases of hook effect encountered with a wi...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-03-01
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Series: | Practical Laboratory Medicine |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S235255172400012X |