Double trouble: Unmasking two hook effects on Siemens Atellica® - Total PSA and total hCG assays

Double trouble: Unmasking two hook effects on Siemens Atellica® - Total PSA and total hCG assays

The “hook effect” or “prozone phenomenon” occurs when the concentration of a particular analyte saturates the antibodies used in the test, resulting in falsely low or negative results despite the presence of high analyte concentrations. We report two recent cases of hook effect encountered with a wi...

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Bibliographic Details
Main Authors: Meryem Benamour, Pauline Brouwers, Arnaud Nevraumont, Tatiana Roy, Jean-Louis Bayart
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Practical Laboratory Medicine
Subjects:
Hook effect
Immunoassay
Interferences
Atellica®
Total PSA
Total HCG
Online Access:http://www.sciencedirect.com/science/article/pii/S235255172400012X

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