Kinetoplastid membrane protein-11 is present in promastigotes and amastigotes of Leishmania amazonensis and its surface expression increases during metacyclogenesis

Kinetoplastid membrane protein-11 is present in promastigotes and amastigotes of Leishmania amazonensis and its surface expression increases during metacyclogenesis

Kinetoplastid membrane protein-11 (KMP-11), a protein present in all kinetoplastid protozoa, is considered a potential candidate for a leishmaniasis vaccine. A suitable leishmaniasis vaccine candidate molecule must be expressed in amastigotes, the infective stage for mammals. However, the expression...

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Bibliographic Details
Main Authors: Denise CS Matos, Lanuza AP Faccioli, Léa Cysne-Finkelstein, Paula Mello De Luca, Suzana Corte-Real, Geraldo RG Armôa, Elezer Monte Blanco Lemes, Débora Decote-Ricardo, Sergio CF Mendonça
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2010-05-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Leishmania amazonensis
KMP-11
expression
amastigote
promastigote
metacyclogenesis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000300018

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000300018

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