Licochalcone A suppresses migration and invasion of human hepatocellular carcinoma cells through downregulation of MKK4/JNK via NF-κB mediated urokinase plasminogen activator expression.

Licochalcone A suppresses migration and invasion of human hepatocellular carcinoma cells through downregulation of MKK4/JNK via NF-κB mediated urokinase plasminogen activator expression.

Hepatocellular cell carcinoma (HCC) is one of the most commonly diagnosed cancers worldwide and in Taiwan. Chemoprevention of cancer with dietary bioactive compounds could potentially reverse, suppress, or prevent cancer progression. Licochalcone A (LicA) is a characteristic chalcone of licorice, wh...

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Bibliographic Details
Main Authors: Jen-Pi Tsai, Pei-Ching Hsiao, Shun-Fa Yang, Shu-Ching Hsieh, Da-Tian Bau, Chu-Liang Ling, Chun-Li Pai, Yi-Hsien Hsieh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3899273?pdf=render

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http://europepmc.org/articles/PMC3899273?pdf=render

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