Natural mutation in the regulatory gene (srrG) influences virulence-associated genes and enhances invasiveness in Streptococcus dysgalactiae subsp. equisimilis strains isolated from cases of streptococcal toxic shock syndrome

Natural mutation in the regulatory gene (srrG) influences virulence-associated genes and enhances invasiveness in Streptococcus dysgalactiae subsp. equisimilis strains isolated from cases of streptococcal toxic shock syndrome

Summary: Background: Streptococcus dysgalactiae subspecies equisimilis (SDSE) has emerged as an important cause of severe invasive infections including streptococcal toxic shock syndrome (STSS). The present study aimed to identify genes involved in differences in invasiveness between STSS and non-i...

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Bibliographic Details
Main Authors: Tadayoshi Ikebe, Hitoshi Otsuka, Kazuki Chiba, Yu Kazawa, Takahiro Yamaguchi, Rumi Okuno, Yoshimi Date, Mari Sasaki, Junko Isobe, Makoto Ohnishi, Yukihiro Akeda
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:EBioMedicine
Subjects:
Streptococcus dysgalactiae subspecies equisimilis
Streptococcus toxic shock syndrome
Mutation
Invasive infections
Bacterial infection
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422003140

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http://www.sciencedirect.com/science/article/pii/S2352396422003140

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