Humoral and T cell responses to SARS-CoV-2 reveal insights into immunity during the early pandemic period in Pakistan

Humoral and T cell responses to SARS-CoV-2 reveal insights into immunity during the early pandemic period in Pakistan

Abstract Background Protection against SARS-CoV-2 is mediated by humoral and T cell responses. Pakistan faced relatively low morbidity and mortality from COVID-19 through the pandemic. To examine the role of prior immunity in the population, we studied IgG antibody response levels, virus neutralizin...

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Bibliographic Details
Main Authors: Kiran Iqbal Masood, Shama Qaiser, Syed Hani Abidi, Erum Khan, Syed Faisal Mahmood, Areeba Hussain, Zara Ghous, Khekahsan Imtiaz, Natasha Ali, Muhammad Hasan, Haris Ali Memon, Maliha Yameen, Shiza Ali, Sadaf Baloch, Gulzar Lakhani, Paula M. Alves, Najeeha Talat Iqbal, Kumail Ahmed, Junaid Iqbal, Zulfiqar A. Bhutta, Rabia Hussain, Martin Rottenberg, J. Pedro Simas, Marc Veldhoen, Kulsoom Ghias, Zahra Hasan
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Infectious Diseases
Subjects:
Spike
Receptor binding domain
SARS-CoV-2
IgG
T cells
Interferon-gamma
Online Access:https://doi.org/10.1186/s12879-023-08829-1

Internet

https://doi.org/10.1186/s12879-023-08829-1

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