The 6-hydroxydopamine model and parkinsonian pathophysiology: Novel findings in an older model
The neurotoxin 6-hydroxydopamine (6-OHDA) is widely used to induce models of Parkinson's disease (PD). We now know that the model induced by 6-OHDA does not include all PD symptoms, although it does reproduce the main cellular processes involved in PD, such as oxidative stress, neurodegeneratio...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier España
2017-10-01
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| Series: | Neurología (English Edition) |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S217358081730113X |