Preoperative radiation dose escalation for rectal cancer using a concomitant boost strategy improves tumor downstaging without increasing toxicity: A matched-pair analysis

Preoperative radiation dose escalation for rectal cancer using a concomitant boost strategy improves tumor downstaging without increasing toxicity: A matched-pair analysis

Purpose: Pathologic complete response to neoadjuvant chemoradiation therapy (CRT) is associated with improved outcomes for patients with locally advanced rectal cancer (LARC). Increased response rates have been reported with higher radiation doses, but these studies often lack long-term outcome and/...

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Main Authors: Jillian R. Gunther, MD, PhD, Awalpreet S. Chadha, MD, Ui Sup Shin, MD, In Ja Park, MD, Kiran V. Kattepogu, MD, Jonathan D. Grant, MD, David C. Weksberg, MD, PhD, Cathy Eng, MD, Scott E. Kopetz, MD, PhD, Prajnan Das, MD, MS, MPH, Marc E. Delclos, MD, Harmeet Kaur, MD, Dipen M. Maru, MD, John M. Skibber, MD, Miguel A. Rodriguez-Bigas, MD, Y. Nancy You, MD, Sunil Krishnan, MD, George J. Chang, MD, MS
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Advances in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S245210941730057X

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http://www.sciencedirect.com/science/article/pii/S245210941730057X

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