Investigation of the Effect of PD-L1 Blockade on Triple Negative Breast Cancer Cells Using Fourier Transform Infrared Spectroscopy

Investigation of the Effect of PD-L1 Blockade on Triple Negative Breast Cancer Cells Using Fourier Transform Infrared Spectroscopy

Interactions between programmed death-1 (PD-1) with its ligand PD-L1 on tumor cells can antagonize T cell responses. Inhibiting these interactions using immune checkpoint inhibitors has shown promise in cancer immunotherapy. MDA-MB-231 is a triple negative breast cancer cell line that expresses PD-L...

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Bibliographic Details
Main Authors: Mohamed H. M. Ali, Salman M Toor, Fazle Rakib, Raghvendra Mall, Ehsan Ullah, Kamal Mroue, Prasanna R. Kolatkar, Khalid Al-Saad, Eyad Elkord
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Vaccines
Subjects:
breast cancer
tumor cells
spectroscopy
FTIR
biochemical alterations
chemometric analysis
Online Access:https://www.mdpi.com/2076-393X/7/3/109

Internet

https://www.mdpi.com/2076-393X/7/3/109

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