Diosmin ameliorates renal fibrosis through inhibition of inflammation by regulating SIRT3-mediated NF-κB p65 nuclear translocation

Diosmin ameliorates renal fibrosis through inhibition of inflammation by regulating SIRT3-mediated NF-κB p65 nuclear translocation

Abstract Background Renal fibrosis is considered an irreversible pathological process and the ultimate common pathway for the development of all types of chronic kidney diseases and renal failure. Diosmin is a natural flavonoid glycoside that has antioxidant, anti-inflammatory, and antifibrotic acti...

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Bibliographic Details
Main Authors: Wen-Man Zhao, Xun-Liang Li, Yuyu Zhu, Rui Shi, Zhi-Juan Wang, Jian-Ping Xiao, De-Guang Wang
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Diosmin
Fibrosis
Inflammation
NF-κB p65
UUO
SIRT3
Online Access:https://doi.org/10.1186/s12906-023-04330-z

Internet

https://doi.org/10.1186/s12906-023-04330-z

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