Identification of the mitochondrial protein POLRMT as a potential therapeutic target of prostate cancer

Abstract RNA polymerase mitochondria (POLRMT) is essential for mitochondrial transcription machinery and other mitochondrial functions. Its expression and potential functions in prostate cancer were explored here. The Cancer Genome Atlas prostate cancer cohort (TCGA PRAD) shows that POLRMT mRNA expr...

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Bibliographic Details
Main Authors: Xiaojun Li, Linya Yao, Tao Wang, Xiaolei Gu, Yufan Wu, Ting Jiang
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06203-2