Germline IgM predicts T cell immunity to Pneumocystis
Pneumocystis is the most common fungal pulmonary infection in children under the age of 5 years. In children with primary immunodeficiency, Pneumocystis often presents at 3–6 months of age, a time period that coincides with the nadir of maternal IgG and when IgM is the dominant Ig isotype. Because B...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Clinical investigation
2022-09-01
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Series: | JCI Insight |
Subjects: | |
Online Access: | https://doi.org/10.1172/jci.insight.161450 |