Germline IgM predicts T cell immunity to Pneumocystis

Pneumocystis is the most common fungal pulmonary infection in children under the age of 5 years. In children with primary immunodeficiency, Pneumocystis often presents at 3–6 months of age, a time period that coincides with the nadir of maternal IgG and when IgM is the dominant Ig isotype. Because B...

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Bibliographic Details
Main Authors: Kristin Noell, Guixiang Dai, Dora Pungan, Anna Ebacher, Janet E. McCombs, Samuel J. Landry, Jay K. Kolls
Format: Article
Language:English
Published: American Society for Clinical investigation 2022-09-01
Series:JCI Insight
Subjects:
Online Access:https://doi.org/10.1172/jci.insight.161450