MGAT2 deficiency ameliorates high-fat diet-induced obesity and insulin resistance by inhibiting intestinal fat absorption in mice

MGAT2 deficiency ameliorates high-fat diet-induced obesity and insulin resistance by inhibiting intestinal fat absorption in mice

<p>Abstract</p> <p>Background</p> <p>Resynthesis of triglycerides in enterocytes of the small intestine plays a critical role in the absorption of dietary fat. Acyl-CoA:monoacylglycerol acyltransferase-2 (MGAT2) is highly expressed in the small intestine and catalyzes t...

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Bibliographic Details
Main Authors: Tsuchida Takuma, Fukuda Sayaka, Aoyama Hisanori, Taniuchi Nobuhiko, Ishihara Tomomi, Ohashi Noriko, Sato Hiroko, Wakimoto Koji, Shiotani Masaharu, Oku Akira
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Lipids in Health and Disease
Subjects:
Acyl-coenzyme A:monoacylglycerol acyltransferase (MGAT)
Obesity
Insulin resistance
Triglyceride
Enterocyte
Fatty acid oxidation
Online Access:http://www.lipidworld.com/content/11/1/75

Internet

http://www.lipidworld.com/content/11/1/75

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