<i>ITGB6</i>-Knockout Suppresses Cholangiocarcinoma Cell Migration and Invasion with Declining PODXL2 Expression

<i>ITGB6</i>-Knockout Suppresses Cholangiocarcinoma Cell Migration and Invasion with Declining PODXL2 Expression

Intrahepatic cholangiocarcinoma (iCCA) is a heterogeneous bile duct cancer with a poor prognosis. Integrin αvβ6 (β6) has been shown to be upregulated in iCCA and is associated with its subclassification and clinicopathological features. In the present study, two <i>ITGB6</i>-knockout HuC...

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Bibliographic Details
Main Authors: Yurie Soejima, Miho Takeuchi, Nao Miyamoto, Motoji Sawabe, Toshio Fukusato
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
cholangiocarcinoma
integrin
<i>ITGB6</i>
CRISPR/Cas9
RNA-seq
PODXL2
Online Access:https://www.mdpi.com/1422-0067/22/12/6303

Internet

https://www.mdpi.com/1422-0067/22/12/6303

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