Functional paclitaxel-manganese-doped mesoporous silica nanoparticles for orthotopic brain glioma targeted therapy

Brain glioma is a highly comorbid tumor with high mortality. In this study, plasma complex component-functionalized manganese-doped mesoporous silica nanoparticles (PMMSN) were prepared and loaded with paclitaxel (PTX) by adsorption for brain glioma treatment. The nanodrug delivery system crossed th...

Full description

Bibliographic Details
Main Authors: Ying Liu, Shengxue Yu, Xue Jiang, Qian Wu, Wenwen Shen, Zhiru Zou, Wei Wei, Chao Wu, Yu Gao
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Materials & Design
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S026412752400087X