The COMPASS Complex Regulates Fungal Development and Virulence through Histone Crosstalk in the Fungal Pathogen <i>Cryptococcus neoformans</i>

The COMPASS Complex Regulates Fungal Development and Virulence through Histone Crosstalk in the Fungal Pathogen <i>Cryptococcus neoformans</i>

The Complex of Proteins Associated with Set1 (COMPASS) methylates lysine K4 on histone H3 (H3K4) and is conserved from yeast to humans. Its subunits and regulatory roles in the meningitis-causing fungal pathogen <i>Cryptococcus neoformans</i> remain unknown. Here we identified the core s...

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Bibliographic Details
Main Authors: Ruoyan Liu, Xiaoyu Chen, Fujie Zhao, Yixuan Jiang, Zhenguo Lu, Huining Ji, Yuanyuan Feng, Junqiang Li, Heng Zhang, Jianting Zheng, Jing Zhang, Youbao Zhao
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Journal of Fungi
Subjects:
COMPASS
H3K4 methylation
H2B ubiquitination
<i>Cryptococcus neoformans</i>
yeast-to-hypha transition
virulence
Online Access:https://www.mdpi.com/2309-608X/9/6/672

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https://www.mdpi.com/2309-608X/9/6/672

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