The Optic Nerve at Stake: Update on Environmental Factors Modulating Expression of Leber’s Hereditary Optic Neuropathy

Optic neuropathies are characterized by the degeneration of the optic nerves and represent a considerable individual and societal burden. Notably, Leber’s hereditary optic neuropathy (LHON) is a devastating vision disease caused by mitochondrial gene mutations that hinder oxidative phosphorylation a...

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Bibliographic Details
Main Authors: Pierre Layrolle, Christophe Orssaud, Maryse Leleu, Pierre Payoux, Stéphane Chavanas
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/12/3/584