High-Throughput Mutation Profiling Changes before and 3 Weeks after Chemotherapy in Newly Diagnosed Breast Cancer Patients.

Changes in tumor DNA mutation status during chemotherapy can provide insights into tumor biology and drug resistance. The purpose of this study is to analyse the presence or absence of mutations in cancer-related genes using baseline breast tumor samples and those obtained after exposure to one cycl...

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Bibliographic Details
Main Authors: Sing-Huang Tan, Nur Sabrina Sapari, Hui Miao, Mikael Hartman, Marie Loh, Wee-Joo Chng, Philip Iau, Shaik Ahmad Buhari, Richie Soong, Soo-Chin Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4667877?pdf=render