Association of the sirtuin and mitochondrial uncoupling protein genes with carotid plaque.

Sirtuins (SIRTs) and mitochondrial uncoupling proteins (UCPs) have been implicated in cardiovascular diseases through the control of reactive oxygen species production. This study sought to investigate the association between genetic variants in the SIRT and UCP genes and carotid plaque.In a group o...

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Bibliographic Details
Main Authors: Chuanhui Dong, David Della-Morte, Liyong Wang, Digna Cabral, Ashley Beecham, Mark S McClendon, Corneliu C Luca, Susan H Blanton, Ralph L Sacco, Tatjana Rundek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3210138?pdf=render