Ganglioside lipidomics of CNS myelination using direct infusion shotgun mass spectrometry

Ganglioside lipidomics of CNS myelination using direct infusion shotgun mass spectrometry

Summary: Gangliosides are present and concentrated in axons and implicated in axon-myelin interactions, but how ganglioside composition changes during myelin formation is not known. Here, we present a direct infusion (shotgun) lipidomics method to analyze gangliosides in small amounts of tissue repr...

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Bibliographic Details
Main Authors: Martina Arends, Melanie Weber, Cyrus Papan, Markus Damm, Michal A. Surma, Christopher Spiegel, Minou Djannatian, Shengrong Li, Lisa Connell, Ludger Johannes, Martina Schifferer, Christian Klose, Mikael Simons
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:iScience
Subjects:
Neuroscience
Cell biology
Omics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222015954

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http://www.sciencedirect.com/science/article/pii/S2589004222015954

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