Metabolomics Profiling As a Diagnostic Tool in Severe Traumatic Brain Injury

Traumatic brain injury (TBI) is a complex disease with a multifaceted pathophysiology. Impairment of energy metabolism is a key component of secondary insults. This phenomenon is a consequence of multiple potential mechanisms including diffusion hypoxia, mitochondrial failure, and increased energy n...

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Bibliographic Details
Main Authors: Jussi P. Posti, Alex M. Dickens, Matej Orešič, Tuulia Hyötyläinen, Olli Tenovuo
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Neurology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2017.00398/full