Transcriptional read-through of the long non-coding RNA SVALKA governs plant cold acclimation

The function of most lncRNA is unknown. Here, the authors show that transcriptional read-through at the Arabidopsis SVALKA locus produces a cryptic lncRNA that overlaps with the neighboring cold-responsive CBF1 gene and limits CBF1 expression via an RNA polymerase II collision-based mechanism.

Bibliographic Details
Main Authors: Peter Kindgren, Ryan Ard, Maxim Ivanov, Sebastian Marquardt
Format: Article
Language:English
Published: Nature Portfolio 2018-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07010-6