XIAP’s Profile in Human Cancer

XIAP, the X-linked inhibitor of apoptosis protein, regulates cell death signaling pathways through binding and inhibiting caspases. Mounting experimental research associated with XIAP has shown it to be a master regulator of cell death not only in apoptosis, but also in autophagy and necroptosis. As...

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Bibliographic Details
Main Authors: Huailu Tu, Max Costa
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/11/1493